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- beauty pageant: Señorita Panamá
- edition: 54th
- venue: MEDCOM studio Panama City, Panama
- dates: April 9, 2020, August 11, 2020, October 9, 2020, February 5, 2021
- host: Alex Medela
- broadcaster: Telemetro
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WINNERS
| PLACEMENT | 2020 | 2019 |
| 2nd runner-up | N/A | Ana Lucia Tejeira Cocle |
| 1st runner-up | N/A | N/A |
| Miss Panama Grand Miss Grand Panama | Angie Keith Bocas del Toro appointed on October 9, 2020 | Carmen Drayton Portobelo |
| Miss Panama Supranacional Miss Supranational Panama | Darelys Yahel Santos Domínguez Panama Norte appointed on October 9, 2020 | N/A |
| Miss Panama Internacional Miss International Panama | Valeria Estefanía Franceschi Alvarado Panama Centro appointed on February 5, 2021 | Betzaida Rodriguez Los Santos |
| Miss Panama Miss Universe Panama | Carmen Isabel Jaramillo Panama Este appointed on April 9, 2020, officially crowned on August 11, 2020 | Mehr Eliezer Isla Flamenco |
CONAN Daily 