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- beauty pageant: Miss Universo Panama
- edition: 1st
- date: May 25, 2022
- venue: Teatro Gladys Vidal & Centro de Convenciones Vasco Núñez de Balboa, Panama City, Panama
- international membership: Miss Universe
- national director: Ricardo Canto
- broadcaster: RPC-TV Panamá
- hosts: Ricardo Canto, Andrea Batista, Jorge Herrera, Kiara Sang
- judges: Claudia De Villalba, Eduardo Lowe, Gladys Brandao, David Bobadilla, Gina Faarup De Cochez, Rina Laxman Aswani
- candidates: 10
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FINALISTS
| PLACEMENT | NAME, AGE, HOMETOWN |
| Top 10 | Gabriela Alejandra Hernández Gómez, 23, Panama City Hazel Nair Quinn García, 22, Panama City Lilena Lourdes Rodríguez González, 22, María José Pérez Alonzo, 18, Panama City Shatzelym Rodríguez Campos, 19, Panama City Walkiria Isabel Reina Sánchez, 23, Panama City Yarielis Noemy Díaz Vega, 18, Panama City |
| Top 3 | Adaluz Perea Vieto, 27, Penonome, Coclé Alina López Reyna, 25, Panama City Solaris de la Luna Barba Cañizales, 23, Chitré, Herrera |
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SPECIAL AWARDS
| AWARD | CANDIDATE |
| Miss Congeniality | |
| Miss Photogenic |
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WINNERS
| PLACEMENT | 2022 | 2021 |
| 2nd runner-up | Adaluz Perea Vieto Penonome, Coclé | N/A |
| 1st runner-up | Alina López Reyna Panama City | N/A |
| Miss Universe Panama | Solaris Barba Chitré, Herrera | Brenda Smith Lezama Panama Centro Señorita Panamá 2021 |
CONAN Daily 