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- beauty pageant: Miss South Africa
- edition: 65th
- date: October 16, 2021
- venue: Grand West Arena, Sun International, Cape Town, South Africa
- hosts: Zozibini Tunzi, Catriona Gray, Nico Panagio, Anele Mdoda
- broadcasters: M-Net, Mzansi Magic, DStv
- number of candidates: 30
JUDGES
- actress Shannon Esra
- television and radio personality Dineo Ranaka
- University of Cape Town vice chancellor Mamokgethi Phakeng
- Miss South Africa 1994 Basetsana Kumalo
- Miss Universe 2015 Pia Wurtzbach
- Miss South Africa 2018 Tamaryn Green
- Miss Universe 2020 Andrea Meza
.
TOP 30
- Andile Mazibuko, 23, KwaZulu-Natal
- Ané Oosthuysen, 23, Gauteng
- Bianca Bezuidenhout, 22, Western Cape
- Catherine Groenewald, 23, Western Cape
- Cheneil Hartzenberg, 24, Gauteng
- Danielle Marais, 24, Gauteng
- Eloïse van der Westhuizen, 26, Western Cape
- Ferini Dayal, 26, Gauteng
- Itumeleng Baloyi, 23, Limpopo
- Jamie Cloete, 23, Western Cape
- Jeanni Mulder, 24, Western Cape
- Kaylan Matthews, 25, Eastern Cape
- Keashel van der Merwe, 22, Gauteng
- Kgaketsang Mathobisa, 22, Free State
- Kgatlhiso Modisane, 27, Gauteng
- Kgothatso Dithebe, 26, Gauteng
- Lalela Mswane, 24, KwaZulu-Natal
- Lehlogonolo Machaba, 24, North West
- Licalle Isaacs, 21, Western Cape
- Lisanne Lazarus, 25, KwaZulu-Natal
- Mawusive Sibutha, 24, Eastern Cape
- Moratwe Masima, 24, Gauteng
- Olin-Shae De La Cruz, 27, Gauteng
- Pearl Ntshehi, 24, Gauteng
- Precious Mndalama, 23, Gauteng
- Pumeza Zibi, 24, Western Cape
- Savannah De Almeida, 23, KwaZulu-Natal
- Tiffany Francis, 22, Gauteng
- Tshegofatso Molefe, 26, Free State
- Zimi Mabunzi, 26, Eastern Cape
.
TOP 10
- Moratwe Masima, 24, Gauteng
- Cheneil Hartzenberg, 24, Gauteng
- Kgothatso Dithebe, 26, Gauteng
- Jeanni Mulder, 24, Western Cape
- Kaylan Matthews, 25, Eastern Cape
- Bianca Bezuidenhout, 22, Western Cape
- Lalela Mswane, 24, KwaZulu-Natal
- Catherine Groenewald, 23, Western Cape
- Tiffany Francis, 22, Gauteng
- Zimi Mabunzi, 26, Eastern Cape
.
SPECIAL AWARD
- Miss Fitness: Kaylan Matthews (Eastern Cape)
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WINNERS
| PLACEMENT | 2021 | 2020 |
| Top 5 | Bianca Bezuidenhout (Western Cape) Jeanni Mulder (Western Cape) | Melissa Nayimuli (Eastern Cape) Lebogang Mahlangu Gauteng |
| Top 3 | Moratwe Masima (Gauteng) Zimi Mabunzi (Eastern Cape) | |
| 2nd runner-up | N/A | Natasha Joubert (Gauteng) *Miss Universe South Africa 2020 |
| 1st runner-up | N/A | Thato Mosehle (North West) *Miss Supranational South Africa 2021 |
| MISS SOUTH AFRICA | Lalela Mswane (KwaZulu-Natal) | Shudufhadzo Musida (Limpopo) *Miss World South Africa 2021 |
Categories: Africa, beauty pageant results, beauty pageants, Entertainment, LISTS, South Africa
